Hypertension: Is A Natural ACE Inhibitor A Key Factor Fighting High Blood Pressure?

Thursday, July 15th, 2021

Introduction

According to the World Health Organisation (WHO), more than 1.13 billion people globally are affected with Hypertension. Unhealthy diets, lack of physical exercise, consumption of alcohol & tobacco, and excess stress are the main contributing factors of Hypertension.

Many individuals suffering from high blood pressure are required to take antihypertensive drugs to keep blood pressure at normal levels. The primary mechanism of action of antihypertensive drugs commonly used is the ACE inhibitor. However, many synthetic ACE inhibitors (e.g. captopril) may cause side effects such as taste alterations, dry cough, and skin rashes. In addition, poor bioavailability and insufficient effectiveness have also become major drawbacks of antihypertensive drugs. The question now to ask is: Is it possible to find a natural and ACE inhibitor in the easily accessible dietary supplement form?

ClamBP™: The Kidney Health Guardian from Ocean and Support for Blood Pressure

At Chenland, we have found the answer to this question in the ocean. Chenland’s R&D team has recently focused on this potential source to help alleviate hypertension by balancing blood pressure, increasing vascular endothelial factors, and promoting overall heart and kidney health.

To understand ClamBP™, we need to start with the concept of “peptides”. Marine peptides are made from high-protein fish species and shellfish as the main raw materials. Studies indicate that the peptides acquired after hydrolysis of clams exhibited various antioxidant, anticancer, antibacterial, and anti-hypertension properties. These ingredients hold pure natural active properties of marine peptides found within functional beverages and healthy foods whose peptides have been favored by customers all over the world, with a continuously increasing market demand.

The brand-new patent extract ClamBP™ is a natural marine active peptide derived from high quality clam meat by our eco-friendly patented bionic enzymolysis technology.

 

Health Benefits

  • Helps improve the glomerular structure changes, inflammation, and collagen deposition
  • Helps improve the kidney health with hypertension
  • Lowers blood pressure moderately
  • Promotes blood circulation and metabolism
  • Improves Heart and Vessel health

 

Our Patented Definition of Science

A number of studies have confirmed that ClamBP™ can effectively inhibit ACE activity in the body and help achieve a long-lasting effect in hypertension relief. ClamBP™ is clinically proven to be safe and effective natural solution for hypertensive kidney damage, and utilises a natural marine ingredient so as to avoid the risk of excess side effects caused by heavy medications. Additionally, it promotes blood circulation and metabolism, which provides a powerful boost to overall heart and blood vessel health.

 

  • Pre-Clinical Study

The detection of BUN (Blood Urea Nitrogen) can provide a basis for the assessment of kidney damage. Compared to the placebo, ClamBPTM can decrease the concentration of BUN effectively.

ClamBPTM can reduce the concentration of ACE and increase the concentration of ACE2 in kidney in SHRs, indicating that ClamBPTM can effectively prevent kidney damage and protect kidney health.

  • Clinical Study

The results of a 6-week open-label clinical study showed that ClamBPTM is safe and effective in lowing high blood pressure. Results showed that systolic blood pressure (SBP) decreased from grade I hypertension to normal blood pressure with diastolic blood pressure results returning to normal.

 

  • Mechanism of Action

ClamBPTM significantly reduced systolic and diastolic blood pressure, and relieved kidney damage by specifically inhibiting the expression of RAS-related pathway factors, regulating the concentration of key biomarkers such as ACE\ACE2\Ang-II in blood and kidney tissues, and overall protecting kidney function and helping lower blood pressure.

 

Chenland: Creating Innovative Health Solutions From TCM

Chenland Nutritionals, Inc. selects only globally certified GAP herbs and marine organisms to ensure our ingredient’s safety, quality, and sustainability. As the leading supplier of natural branded ingredients, Chenland uses complementary and alternative medicine as the theoretical basis to make the innovative collision of traditional medicine and modern technology come true. We strive to revitalise the multitude of benefits traditional medicine can provide by combining innovative scientific advancement with clinically backed branded ingredients to ensure the health and well-being for our valuable customers for years to come.

 

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