Affron For Sports Nutrition: Pharmactive

Tuesday, July 12th, 2022 | 870 Views

Pharmactive Biotech Products, S.L.U. moves into sports nutrition

Pharmactive Biotech Products, S.L.U. moves into sports nutrition following results of the latest research on Affron, a natural saffron ingredient. The clinical study demonstrates two important findings: Affron improved enjoyment in sport active adults, and, in males, it can help increase the resilience to stress and anxiety by increasing the cardiac parasympathetic response that regulates post-exercise heart rate.


“While most consumers agree exercise and physical activity are vital, especially after so many have spent too much of the past three years in lockdown, for most people routine exercise three times a week is hard, and often is boring. But if it’s possible to better enjoy the activity, it can create positive feedback that encourages doing more and maintaining a routine much longer,” explains Jean-Marie Raymond, CEO for Pharmactive.


Although previous research demonstrated the pure, clean-label saffron ingredient can help promote better sleep and boost recovery for athletes, results of a new clinical study in Australia revealed that Affron supplementation in recreationally active males was associated with increases in self-reported exercise enjoyment and positive Heart Rate Variability (HRV).The six-week, randomised, double-blind, placebo-controlled trial included healthy, nonprofessional participants, aged 18 to 65 years, who performed moderate-to-intense aerobic exercise more than three times per week. Activities included such exercises as cycling, running, swimming, tennis, aerobics, and/or boxing.


Study subjects were chosen using strict exclusion criteria. 62 volunteers participated in the study, and 59 completed it. Each subject took 14 mg of Affron, two times per day. The researchers provided participants a standard sport wearable to measure HRV, allowing the subjects to engage with their watch and see results daily and in real time. At the end of the trial, the male participants taking Affron demonstrated statistically significant changes compared to the placebo group in heart rate variability (HRV), measured during bedtime.


The HRV is an indicator of recovery as previously revealed in studies on adults with occasional stress and/or burnout, who exhibit decreased HRV. “We decided to use a sports watch in the study model during sleep-time as it offers a very easy to use means measuring heart rate. Using the sports watch, consumers can see for themselves the impact of Affron in real time and in the long term,” notes Raymond.


To measure how much the volunteers enjoyed their workouts, the research team employed the Physical Activity Enjoyment Scale (PAES). Results revealed a statistically significant increase in PAES score over time in the Affron group, with no such increase in the placebo group. This suggests an improvement in enjoyment and mood with daily intake of Affron. “Affron’s positive effect on heart rate and work out enjoyment could be attributed to various physiological mechanisms at play,” adds Alberto Espinel, Head of Strategic R&D in Active and Functional Natural Ingredients for Pharmactive. “Previous animal studies have endorsed it role in reducing stress hormones such as cortisol while raising the “happy hormones” serotonin and dopamine.


The botanical also demonstrated a relaxant effect on smooth muscles and blood vessels. Studies suggest it may even positively interact with the gut flora, which affects the nervous system. Moreover saffron is touted as a potent anti-oxidant anti-inflammatory.” Pharmactive’s Affron is naturally extracted from saffron with full control by the company from farm to shelf. It is water-soluble and versatile across multiple applications, including supplements, powders, and shots. The recommended amount of Affron is 28 mg per day, either enjoyed in a single dose, or split into two 14 mg doses per day.


Pharmactive Partners With Singapore’s Nutraconnect

Pharmactive Biotech Products, S.L.U. has announced a new strategic partnership with Singapore-based Nutraconnect Pte, Ltd. to bring innovative, scientifically backed nutraceutical ingredients to the Asia-Pacific marketplace (excluding Australia and New Zealand). The partnership will combine the strengths of both companies into a greater whole. Pharmactive will provide its well-supported, clean-label botanical extract ingredients, while Nutraconnect will function as a growth engine for the region, connecting Pharmactive with local and regional nutraceutical players seeking high-quality, pure ingredients. Founded in 2022, Nutraconnect Pte., Ltd., is a nutraceutical business growth acceleration service headquartered in Singapore. The company provides end-to-end solutions for global nutraceutical ingredient manufacturers that are looking to establish a foundation for sustainable growth in the fragmented, but booming APAC market.


Jean-Marie Raymond, CEO and Founder of Pharmactive, said, “Asia is a tremendous growth-hub for Pharmactive. We already have had successes in Korea, Japan, Vietnam, and Malaysia with Affron® pure saffron extract and Aged Black Garlic [ABG+®]. Many Asian industry players, formulators, and brand owners approach us about new compounding formats or innovative product concepts to cross the nutraceutical/functional food and beverage divide. Asia is clearly the frontrunner in terms of new ingredient concepts.”


“When it comes to nutraceuticals, Asia-Pacific is a fast-moving region, with multiple players constantly on the lookout for the latest ingredients,” adds Sawant. “They expect great service and rapid response, even with difficult custom-made formulations, questions about the regulatory framework in certain countries, etc., and this is exactly where our core strength lies. We look forward to helping Pharmactive meet challenges and grow its business in the APAC market.”